2-Thiopheneboronic acid → HCID 11667243, compound

HRID 1445814Notes

Reaction equation

HRID 1445814 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1B(O)O.Br[C:10]1[CH:15]=[CH:14][C:13]([C:16]2[O:17][C:18]([CH3:28])=[C:19]([CH2:21][CH2:22][N:23]3[CH2:27][CH2:26][CH2:25][CH2:24]3)[N:20]=2)=[CH:12][CH:11]=1>>[CH3:28][C:18]1[O:17][C:16]([C:13]2[CH:14]=[CH:15][C:10]([C:2]3[S:1][CH:5]=[CH:4][CH:3]=3)=[CH:11][CH:12]=2)=[N:20][C:19]=1[CH2:21][CH2:22][N:23]1[CH2:27][CH2:26][CH2:25][CH2:24]1

Participants

3

Reactant 2

HCID 27339602-Thiopheneboronic acidHCID 116815462-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

Product 1

HCID 11667243HCID 11667243, compound

Procedure

The title compound is prepared in a manner substantially analogous to Example 45 starting from 2-Thiophene boronic acid and 2-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole. MS (m/e): 339.1 (M+1)

Sources & evidence

ORD record
ord-d1b5ede0fbb047a9817a8f23b2f18a1e
Source dataset
uspto-grants-2010_02
Patent number
US07666871B2

Reaction notes

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