4-(Methanesulfonyl)phenylboronic acid → HCID 68704404, compound

HRID 1445842Notes

Reaction equation

HRID 1445842 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:20])=[C:11]([CH2:13][N:14]3[CH2:18][CH2:17][CH2:16][CH:15]3[CH3:19])[N:12]=2)=[CH:4][CH:3]=1.[CH3:21][S:22]([C:25]1[CH:30]=[CH:29][C:28](B(O)O)=[CH:27][CH:26]=1)(=[O:24])=[O:23]>>[CH3:21][S:22]([C:25]1[CH:30]=[CH:29][C:28]([C:2]2[CH:7]=[CH:6][C:5]([C:8]3[O:9][C:10]([CH3:20])=[C:11]([CH2:13][N:14]4[CH2:18][CH2:17][CH2:16][CH:15]4[CH3:19])[N:12]=3)=[CH:4][CH:3]=2)=[CH:27][CH:26]=1)(=[O:24])=[O:23]

Participants

3

Reactant 2

HCID 27343644-(Methanesulfonyl)phenylboronic acidHCID 68706088HCID 68706088, compound

Product 1

HCID 68704404HCID 68704404, compound

Procedure

The titled compound is prepared substantially in accordance with the procedure of Example 9 using 2-(4-Bromo-phenyl)-5-methyl-4-(2-methyl-pyrrolidin-1-ylmethyl)-oxazole (See Example 99) and 4-methylsulfonylphenylboronic acid. MS (m/e) 411.2 (M+1).

Sources & evidence

ORD record
ord-5e4b7652605a40e3a36fad49b78f2bd3
Source dataset
uspto-grants-2010_02
Patent number
US07666871B2

Reaction notes

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