Potassium Carbonate → HCID 68700924, compound

Participants

Reaction Steps

Prepare using the method of Example 103 with palladium (II) acetate (0.002 g, 0.008 mmol), anhydrous acetonitrile (4 mL), triphenylphosphine (0.009 g, 0.034 mmol), distilled water (1 mL), 4-(methanesulfonyl)benzeneboronic acid (0.096 g, 0.45 mmol), (3R)-1-{2-[2-(4-bromophenyl)-5-methyl-1,3-oxazol-4-yl]ethyl}pyrrolidin-3-ol (See Example 106) (0.150 g, 0.43 mmol) and potassium carbonate (0.177 g, 1.28 mmol). Additionally purify using mass guided HPLC to give the title compound as a cream coloured solid (0.034 g): MS (m/e): 427(M+1).

Provenance & Evidence