4-(Bromomethyl)pyridine hbr → HCID 11617773, compound

HRID 1445864Notes

Reaction equation

HRID 1445864 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:22])=[C:11]([CH2:13][C:14]([N:16]3[CH2:20][CH2:19][CH2:18][C@H:17]3[CH3:21])=O)[N:12]=2)=[CH:4][CH:3]=1.Br.Br[CH2:25][C:26]1[CH:31]=[CH:30][N:29]=[CH:28][CH:27]=1>>[CH3:22][C:10]1[O:9][C:8]([C:5]2[CH:6]=[CH:7][C:2]([O:1][CH2:25][C:26]3[CH:31]=[CH:30][N:29]=[CH:28][CH:27]=3)=[CH:3][CH:4]=2)=[N:12][C:11]=1[CH2:13][CH2:14][N:16]1[CH2:20][CH2:19][CH2:18][C@H:17]1[CH3:21]

Participants

3

Reactant 2

HCID 127522194-(Bromomethyl)pyridine hbrHCID 135487319HCID 135487319, compound

Product 1

HCID 11617773HCID 11617773, compound

Procedure

The title compound is prepared in a manner substantially similar to Example 57 from 2-[2-(4-Hydroxy-phenyl)-5-methyl-oxazol-4-yl]-1-(2-(R)-methyl-pyrrolidin-1-yl)-ethanone (See Example 56) and 4-(bromomethyl)pyridine hydrobromide. MS (m/e): 378.3 (M+1)

Sources & evidence

ORD record
ord-08020c440e2543b097d66e2e9dbd75de
Source dataset
uspto-grants-2010_02
Patent number
US07666871B2

Reaction notes

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