6-Chloromethyl-2-methylpyridinium chloride → HCID 11625312, compound

HRID 1445865Notes

Reaction equation

HRID 1445865 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:22])=[C:11]([CH2:13][C:14]([N:16]3[CH2:20][CH2:19][CH2:18][C@H:17]3[CH3:21])=O)[N:12]=2)=[CH:4][CH:3]=1.Cl.Cl[CH2:25][C:26]1[CH:31]=[CH:30][CH:29]=[C:28]([CH3:32])[N:27]=1>>[CH3:25][C:26]1[CH:31]=[CH:30][CH:29]=[C:28]([CH2:32][O:1][C:2]2[CH:7]=[CH:6][C:5]([C:8]3[O:9][C:10]([CH3:22])=[C:11]([CH2:13][CH2:14][N:16]4[CH2:20][CH2:19][CH2:18][C@H:17]4[CH3:21])[N:12]=3)=[CH:4][CH:3]=2)[N:27]=1

Participants

3

Reactant 2

HCID 765456-Chloromethyl-2-methylpyridinium chlorideHCID 135487319HCID 135487319, compound

Product 1

HCID 11625312HCID 11625312, compound

Procedure

The title compound is prepared in a manner substantially similar to Example 58 from 2-[2-(4-Hydroxy-phenyl)-5-methyl-oxazol-4-yl]-1-(2-(R)-methyl-pyrrolidin-1-yl)-ethanone (See Example 56) and 2-chloromethyl-6-methyl-pyridine hydrochloride [CAS 3099-30-7]. MS (m/e): 392.3 (M+1)

Sources & evidence

ORD record
ord-eb9f1a038da741798894774b16fbc4af
Source dataset
uspto-grants-2010_02
Patent number
US07666871B2

Reaction notes

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