HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 11642261, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 17beta-Hydroxy wortmannin | HCID 9867340 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 11642261 | HCID 11642261 | 29.8% |
Reaction Steps
To a solution of 50 mg (0.12 mmol) 17-hydroxywortmannin in 0.5 mL CH2Cl2 is added 24 mg (0.24 mmol) 1-methylpiperazine. The reaction mixture is stirred at room temperature overnight. CH2Cl2 is removed in vacuo. The residue is triturated with Et2O to give 19 mg (29.8%) product as an orange powder. MS (ESI) m/z 531.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666901B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-2fb17f0147644209bff2cd5147880a8a |
| Source note | uspto-grants-2010_02 |