Water → HCID 68542308, compound

Participants

Reaction Steps

To a solution of 100 mg (0.23 mmol) 17-hydroxywortmannin in 2 mL CH2Cl2 is added 100 mg of ethylamine hydrochloride and 100 μL triethylamine. The reaction mixture is stirred at room temperature for 24 h. Water is added and the CH2Cl2 is removed, filtered through K2CO3 and concentrated in vacuo. The residue is dissolved in EtOAc and precipitated with hexanes to give a yellow powder (32 mg, 29%). MS (ESI) m/z 476.22813 (M+1).

Provenance & Evidence