HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → diethyl 2-bromo-1-(but-2-ynyl)-1H-imidazole-4,5-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-Bromo-2-butyne | HCID 2756862 | — |
| Reactant | Diethyl 2-bromo-1H-imidazole-4,5-dicarboxylate | HCID 14752650 | — |
| Reactant | dimethyl 2-bromo-1-(3-methyl-2-buten-1-yl)-1H-imidazole-4,5-dicarboxylate | HCID 59815068 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | diethyl 2-bromo-1-(but-2-ynyl)-1H-imidazole-4,5-dicarboxylate | HCID 59815044 | — |
Reaction Steps
Prepared analogously to 1b from 3.50 g (12.02 mmol) diethyl 2-bromo-imidazole-4,5-dicarboxylate with 1.09 ml (12.1 mmol) 1-bromo-2-butyne and 2.07 g (15.00 mmol) potassium carbonate in 15 ml of dimethylformamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07667035B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-64dc521169de4750998c617aad232830 |
| Source note | uspto-grants-2010_02 |