HCID 44242274, compound → HCID 44242339, compound

Participants

Reaction Steps

N-(3-{3-Fluoro-4-[4-methoxy-2-(2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6(S)-yloxy)-pyrimidin-5-yl]-phenyl}-2-oxo-oxazolidin-5(S)-ylmethyl)-acetamide. The title compound was prepared by following the same procedure as described in the preparation of Example 7, except 6(S)-(5-bromo-3-methyl-pyridin-2-yloxy)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine was used in place of 6(S)-(5-bromo-pyridin-2-yloxy)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine. ESI MS m/z 527.3 (M+H+); 1H NMR (400 MHz, CDCl3) δ 7.95 (s, 1H), 7.56 (s, 1H), 7.49 (dd, J=12.8, 2.0 Hz, 1H), 7.38 (s, 1H), 7.32 (t, J=8.4 Hz, 1H), 7.24-7.21 (m, 1H), 5.89 (t, J=6.0 Hz, 1H), 5.73 (s, 1H), 4.78-4.75 (m, 2H), 4.48 (d, J=12.8 Hz, 1H), 4.36 (d, J=2.4 Hz, 2H), 3.76 (dd, J=9.2, 6.8 Hz, 1H), 3.66-3.59 (m, 2H), 2.10 (s, 3H), 1.97 (s, 3H).

Provenance & Evidence