Tavaborole → Methanesulfonic acid 6-(4-fluoro-2-hydroxymethyl-phenyl)-5-[4-(2-piperidin-1-yl-ethoxy)-benzoyl]-naphthalen-2-yl ester
Reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[O:5][c:6]1[cH:7][c:8]2[cH:9][cH:10][c:11]([O:33][S:34]([C:35]([F:36])([F:37])[F:38])(=[O:39])=[O:40])[c:12]([C:16]([c:17]3[cH:18][cH:19][c:20]([O:23][CH2:24][CH2:25][N:26]4[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]4)[cH:21][cH:22]3)=[O:32])[c:13]2[cH:14][cH:15]1.[F:41][c:42]1[cH:43][c:44]2[c:45]([cH:50][cH:51]1)[B:46]([OH:49])[O:47][CH2:48]2.[cH:52]1[cH:53][cH:54][c:55]([P:56]([Pd:57]([P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)([P:77]([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[P:96]([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)([c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)[c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)[cH:127][cH:128]1>>[CH3:1][S:2](=[O:3])(=[O:4])[O:5][c:6]1[cH:7][c:8]2[cH:9][cH:10][c:11](-[c:45]3[c:44]([CH2:48][OH:47])[cH:43][c:42]([F:41])[cH:51][cH:50]3)[c:12]([C:16]([c:17]3[cH:18][cH:19][c:20]([O:23][CH2:24][CH2:25][N:26]4[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]4)[cH:21][cH:22]3)=[O:32])[c:13]2[cH:14][cH:15]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d5bd896980aa4585b836cbec55af9236
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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