1H-1,2,4-Triazole → 4-(1,2,4-Triazol-1-yl)aniline

HRID 1446122Notes

Reaction equation

HRID 1446122 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-])=O)=[CH:4][CH:3]=1.[NH:11]1[CH:15]=[N:14][CH:13]=[N:12]1>>[N:11]1([C:2]2[CH:7]=[CH:6][C:5]([NH2:8])=[CH:4][CH:3]=2)[CH:15]=[N:14][CH:13]=[N:12]1

Participants

3

Reactant 2

HCID 92571H-1,2,4-TriazoleHCID 9590p-Fluoronitrobenzene

Product 1

HCID 7358264-(1,2,4-Triazol-1-yl)aniline

Procedure

The title compound is obtained as described in Example 18a/b using 1-fluoro-4-nitro-benzene (Fluka, Buchs, Switzerland) and 1,2,4-triazole (Fluka, Buchs, Switzerland). Title compound: ES-MS: 161.2 (M+H)+; analytical HPLC: tret=3.29 minutes (Grad 2).

Sources & evidence

ORD record
ord-29734a0b90184b26a6348288d320c547
Source dataset
uspto-grants-2010_02
Patent number
US07667039B2

Reaction notes

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