Pyrrolidine → 5-(4-Fluorophenyl)-4-(pyrrolidin-1-ylcarbonyl)isoxazole

Participants

Reaction Steps

The title compound was prepared from 5-(4-fluorophenyl)isoxazole-4-carboxylic acid (10.4 mg, 0.050 mmol) and pyrrolidine (4.3 mg, 0.060 mmol) as described in synthetic method A and thereafter purified by preparative HPLC method A to give a solid (9.6 mg). MS (pos) m/z 261.1 (M+H).

Provenance & Evidence