HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Ethyl-2-methylpiperidine → 5-Ethyl-2-methyl-1-{[5-(4-methylphenyl)isoxazol-4-yl]carbonyl}piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Ethyl-2-methylpiperidine | HCID 7727 | — |
| Reactant | 5-(p-Tolyl)isoxazole-4-carboxylic acid | HCID 22831706 | — |
| Product | 5-Ethyl-2-methyl-1-{[5-(4-methylphenyl)isoxazol-4-yl]carbonyl}piperidine | HCID 59170085 | — |
Reaction Steps
The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 5-ethyl-2-methylpiperidine (7.6 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (5.5 mg). HRMS calcd for C19H24N2O2: 312.1838, found 312.1841.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-c8c69e2196774e48a5d2b8d2711345b3 |
| Source note | uspto-grants-2010_02 |