N-Ethylpyridine-4-methylamine → HCID 59170184, compound

HRID 1446184Notes

Reaction equation

HRID 1446184 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[CH:10][C:9]=2[C:13]([OH:15])=O)=[CH:4][CH:3]=1.[CH2:16]([NH:18][CH2:19][C:20]1[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=1)[CH3:17]>>[CH2:16]([N:18]([CH2:19][C:20]1[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=1)[C:13]([C:9]1[CH:10]=[N:11][O:12][C:8]=1[C:5]1[CH:4]=[CH:3][C:2]([CH3:1])=[CH:7][CH:6]=1)=[O:15])[CH3:17]

Participants

3

Reactant 2

HCID 96681N-Ethylpyridine-4-methylamineHCID 228317065-(p-Tolyl)isoxazole-4-carboxylic acid

Product 1

HCID 59170184HCID 59170184, compound

Procedure

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 4-(ethylaminomethyl)-pyridine (8.2 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (7.8 mg). HRMS calcd for C19H19N3O2: 321.1477, found 321.1485.

Workup

  1. custompurified by preparative HPLC method B

Sources & evidence

ORD record
ord-6bcbf7c813314bae8cdd8500aef428b3
Source dataset
uspto-grants-2010_02
Patent number
US07666888B2

Reaction notes

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