3-Pyrrolidin-2-ylmethylpyridine dihydrochloride → 3-[(1-{[5-(4-Methylphenyl)isoxazol-4-yl]carbonyl}pyrrolidin-2-yl)methyl]pyridine

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Reaction Steps

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 3-pyrrolidin-2-ylmethylpyridine dihydrochloride (14.1 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (4.7 mg). Calcd for C21H21N3O2: 347.1634, found 347.1635.

Provenance & Evidence