N-Methyl-2-(pyridin-3-yl)ethanamine dihydrochloride → N-Methyl-5-(4-methylphenyl)-N-(2-pyridin-3-ylethyl)isoxazole-4-carboxamide

Participants

Reaction Steps

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 3-[2-(methylamino)ethyl]pyridine dihydrochloride (12.5 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (4.6 mg). Calcd for C19H19N3O2: 321.1477, found 321.1491.

Provenance & Evidence