2,2-Diphenylethylamine → HCID 24809506, compound

HRID 1446201Notes

Reaction equation

HRID 1446201 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[CH:10][C:9]=2[C:13]([OH:15])=O)=[CH:4][CH:3]=1.[C:16]1([CH:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH2:23][NH2:24])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:25]1([CH:22]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:23][NH:24][C:13]([C:9]2[CH:10]=[N:11][O:12][C:8]=2[C:5]2[CH:4]=[CH:3][C:2]([CH3:1])=[CH:7][CH:6]=2)=[O:15])[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

Participants

3

Reactant 2

HCID 775752,2-DiphenylethylamineHCID 228317065-(p-Tolyl)isoxazole-4-carboxylic acid

Product 1

HCID 24809506HCID 24809506, compound

Procedure

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 2,2-diphenylethylamine (11.8 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (4.0 mg). Calcd for C25H22N2O2: 382.1681, found 382.1682.

Workup

  1. custompurified by preparative HPLC method B

Sources & evidence

ORD record
ord-dceb921f0377420da349bc058fbd6f99
Source dataset
uspto-grants-2010_02
Patent number
US07666888B2

Reaction notes

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