3-(4-Chlorobenzyl)pyrrolidine oxalate → 4-{[3-(4-Chlorobenzyl)pyrrolidin-1-yl]carbonyl}-5-(4-methylphenyl)isoxazole

Participants

Reaction Steps

The title compound was prepared from 5-(4-methylphenyl)isoxazole-4-carboxylic acid (10.2 mg, 0.050 mmol) and 3-(4-chlorobenzyl)pyrrolidine oxalate (17.1 mg, 0.060 mmol) as described in synthetic method B and thereafter purified by preparative HPLC method B to give a solid (8.1 mg). Calcd for C22H21ClN2O2: 380.1292, found 380.1295.

Provenance & Evidence