HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Benzylpyrrolidine → 4-[(2-Benzylpyrrolidin-1-yl)carbonyl]-5-(2-chlorophenyl)isoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Benzylpyrrolidine | HCID 339556 | — |
| Reactant | 5-(2-Chlorophenyl)-1,2-oxazole-4-carboxylic acid | HCID 22494276 | — |
| Product | 4-[(2-Benzylpyrrolidin-1-yl)carbonyl]-5-(2-chlorophenyl)isoxazole | HCID 59170170 | — |
Reaction Steps
The title compound was prepared from 5-(2-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and 2-benzylpyrrolidine (9.7 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (9.4 mg). Calcd for C21H19ClN2O2: 366.1135, found 366.1136.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-e4b5f208684a4103930fa538b4afeb4a |
| Source note | uspto-grants-2010_02 |