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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446233Generated: October 31, 2026

3-[(4-Fluorophenyl)methyl]pyrrolidine--hydrogen chloride (1/1) → HCID 59170206, compound

https://huagongshe.com/reaction/1446233

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[(4-Fluorophenyl)methyl]pyrrolidine--hydrogen chloride (1/1)HCID 17749754—
Reactant5-(2-Chlorophenyl)-1,2-oxazole-4-carboxylic acidHCID 22494276—
ProductHCID 59170206HCID 59170206—

Reaction Steps

The title compound was prepared from 5-(2-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and 3-(4-fluorobenzyl)pyrrolidine hydrochloride (12.9 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (10.1 mg). Calcd for C21H18ClFN2O2: 384.1041, found 384.1042.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-a5777b149d534d688ca5f2c08dff7224
Source noteuspto-grants-2010_02