N-Ethylbenzylamine → HCID 59170167, compound

HRID 1446244Notes

Reaction equation

HRID 1446244 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[O:12][N:11]=[CH:10][C:9]=1[C:13]([OH:15])=O.[CH2:16]([NH:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH3:17]>>[CH2:19]([N:18]([CH2:16][CH3:17])[C:13]([C:9]1[CH:10]=[N:11][O:12][C:8]=1[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Cl:1])=[O:15])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 84352N-EthylbenzylamineHCID 224942765-(2-Chlorophenyl)-1,2-oxazole-4-carboxylic acid

Product 1

HCID 59170167HCID 59170167, compound

Procedure

The title compound was prepared from 5-(2-chlorophenyl)isoxazole-4-carboxylic acid (11.2 mg, 0.050 mmol) and N-ethylbenzylamine (8.1 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (8.4 mg). Calcd for C19H17ClN2O2: 340.0979, found 340.0978.

Workup

  1. custompurified by preparative HPLC method B

Sources & evidence

ORD record
ord-9d7a3a384d424fa79c88db6bfeaa33ce
Source dataset
uspto-grants-2010_02
Patent number
US07666888B2

Reaction notes

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