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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446248Generated: November 2, 2026

HCID 17749748, compound → HCID 59170126, compound

https://huagongshe.com/reaction/1446248

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 17749748HCID 17749748—
Reactant4-Isoxazolecarboxylic acid, 5-[4-(trifluoromethyl)phenyl]-HCID 68682921—
ProductHCID 59170126HCID 59170126—

Reaction Steps

The title compound was prepared from 5-(4-trifluoromethylphenyl)isoxazole-4-carboxylic acid (12.9 mg, 0.050 mmol) and 3-(4-chlorophenyl)pyrrolidine oxalate (16.3 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (5.4 mg). Calcd for C21H16ClF3N2O2: 420.0852, found 420.0855.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07666888B2
Source datasetuspto-grants-2010_02
ORD IDord-3b600d3647944b5095a29378ede39138
Source noteuspto-grants-2010_02