3-(4-METHYLPHENYL)PYRROLIDINE OXALATE → 4-{[3-(4-Methylphenyl)pyrrolidin-1-yl]carbonyl}-5-[4-(trifluoromethyl)phenyl]isoxazole

Participants

Reaction Steps

The title compound was prepared from 5-(4-trifluoromethylphenyl)isoxazole-4-carboxylic acid (12.9 mg, 0.050 mmol) and 3-(4-methylphenyl)pyrrolidine oxalate (15.1 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (6.3 mg). Calcd for C22H19F3N2O2: 400.1399, found 400.1400.

Provenance & Evidence