HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-(+)-2-(Methoxymethyl)pyrrolidine → HCID 59170160, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-(+)-2-(Methoxymethyl)pyrrolidine | HCID 671217 | — |
| Reactant | 4-Isoxazolecarboxylic acid, 5-[4-(trifluoromethyl)phenyl]- | HCID 68682921 | — |
| Product | HCID 59170160 | HCID 59170160 | — |
Reaction Steps
The title compound was prepared from 5-(4-trifluoromethylphenyl)isoxazole-4-carboxylic acid (12.9 mg, 0.050 mmol) and (S)-2-methoxymethyl-pyrrolidine (6.9 mg, 0.060 mmol) as described in synthetic method C and thereafter purified by preparative HPLC method B to give a solid (12.8 mg). Calcd for C17H17F3N2O3: 354.1191, found 354.1189.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07666888B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-3702d99cdbd84348938f48fc2295070f |
| Source note | uspto-grants-2010_02 |