1,3-Dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one → HCID 59170164, compound

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Reaction Steps

To 5-(4-methylphenyl)isoxazole-4-carbonyl chloride (10 mg, 0.054 mmol) in dichloromethane (1 mL) was added 1-piperidin-4-yl-1,3-dihydro-2H-benzimidazol-2-one (10 mg, 0.046 mmol, 1 eq.), and the reaction mixture was stirred for 1 h. The solvent was removed, and the residue was purified by preparative reverse-phase HPLC to give the title compound. HRMS (ESI, pos. ion) m/z calcd for C23H22N4O3: 402.1692, found 402.1695.

Provenance & Evidence