HCID 68685083, compound → HCID 59170263, compound

Participants

Reaction Steps

To 5-(4-methylphenyl)isoxazole-4-carbonyl chloride (10 mg, 0.045 mmol) in dichloromethane (1 mL) was added 2-(methylsulfonyl)-2,3-dihydrospiro[isoindole-1,4′-piperidine] (13.2 mg, 0.050 mmol, 1.1 eq), and the reaction mixture was stirred for 1 h. The solvent was removed, and the residue was purified by preparative reverse-phase HPLC to give the title compound. HRMS (ESI, pos. ion) m/z calcd for C24H25N3O4S: 451.1566, found 451.1567.

Provenance & Evidence