3-(4-Piperidinyl)-1H-indole → HCID 59170165, compound

Participants

Reaction Steps

To 5-(4-methylphenyl)isoxazole-4-carbonyl chloride (10 mg, 0.045 mmol) in dichloromethane (1 mL) was added 3-piperidin-4-yl-1H-indole (9.9 mg, 0.050 mmol, 1.1 eq.), and the reaction mixture was stirred for 1 h. The solvent was removed, and the residue was purified by preparative reverse-phase HPLC to give the title compound. HRMS (ESI, pos. ion) m/z calcd for C24H23N3O2: 385.1790, found 385.1797.

Provenance & Evidence