Methanol → N-{4-[(2-{[2-fluoro-5-(trifluoromethyl)phenyl]amino}-1-methyl-1H-benzimidazol-5-yl)oxy]pyridin-2-yl}-3-(1-methylpiperidin-4-yl)propanamide
Reaction equation
[C:41]([BH3-:42])#[N:43].[CH3:45][OH:46].[F:1][c:2]1[c:3]([NH:12][c:13]2[n:14][c:15]3[c:16]([n:17]2[CH3:18])[cH:19][cH:20][c:21]([O:23][c:24]2[cH:25][c:26]([NH:30][C:31]([CH2:32][CH2:33][CH:34]4[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]4)=[O:40])[n:27][cH:28][cH:29]2)[cH:22]3)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1.[Na+:44]>>[F:1][c:2]1[c:3]([NH:12][c:13]2[n:14][c:15]3[c:16]([n:17]2[CH3:18])[cH:19][cH:20][c:21]([O:23][c:24]2[cH:25][c:26]([NH:30][C:31]([CH2:32][CH2:33][CH:34]4[CH2:35][CH2:36][N:37]([CH3:41])[CH2:38][CH2:39]4)=[O:40])[n:27][cH:28][cH:29]2)[cH:22]3)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-2b7cf05d84d64001bf2eda6c4f5f4dea
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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