Imidazo[1,2-a]pyridin-7-ylboronic acid pinacol ester → HCID 68541679, compound

HRID 1446710Notes

Reaction equation

HRID 1446710 reaction equation
Cl[C:2]1[N:7]=[C:6]([CH2:8][C:9](=[O:11])[CH3:10])[CH:5]=[CH:4][CH:3]=1.CC1(C)C(C)(C)OB([C:20]2[CH:25]=[CH:24][N:23]3[CH:26]=[CH:27][N:28]=[C:22]3[CH:21]=2)O1>>[N:28]1[CH:27]=[CH:26][N:23]2[CH:24]=[CH:25][C:20]([C:2]3[N:7]=[C:6]([CH2:8][C:9](=[O:11])[CH3:10])[CH:5]=[CH:4][CH:3]=3)=[CH:21][C:22]=12

Participants

3

Reactant 2

HCID 49758473Imidazo[1,2-a]pyridin-7-ylboronic acid pinacol esterHCID 826531441-(6-Chloropyridin-2-yl)propan-2-one

Product 1

HCID 68541679HCID 68541679, compound

Procedure

Prepare from 1-(6-chloro-pyridin-2-yl)-propan-2-one and 7-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-imidazo[1,2-a]pyridine using conditions similar to Preparation 21 step A. MS(ES), m/z 170 (M+1).

Sources & evidence

ORD record
ord-3dfad24be499499ca68e0c37b95f51ba
Source dataset
uspto-grants-2010_02
Patent number
US07666879B2

Reaction notes

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