tert-Butanol → 4-(1-Pyrimidin-2-ylpiperidin-4-ylamino)benzoic acid tert-butyl ester
Reaction equation
[Br:1][c:2]1[n:3][cH:4][cH:5][cH:6][n:7]1.[C:28]([OH:29])([CH3:30])([CH3:31])[CH3:32].[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13]([c:14]1[cH:15][cH:16][c:17]([NH:20][CH:21]2[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]2)[cH:18][cH:19]1)=[O:27]>>[c:2]1([N:24]2[CH2:23][CH2:22][CH:21]([NH:20][c:17]3[cH:16][cH:15][c:14]([C:13]([O:12][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:27])[cH:19][cH:18]3)[CH2:26][CH2:25]2)[n:3][cH:4][cH:5][cH:6][n:7]1Participants
4
Sources & evidence
- ORD record
- ord-9364a6a68a164fcdba5c38ec1c26706d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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