HRID1446731

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)c1cc(NC(=O)OCC(Cl)(Cl)Cl)n(CCO[Si](C)(C)C(C)(C)C)n1

HCID68542210

未命名化合物

结构：CS(=O)(=O)c1ccc(-c2ccn3c(-c4ccc(CN)cc4)cnc3c2)cc1

HCID68546107

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1cc(NC(=O)NCc2ccc(-c3cnc4cc(-c5ccc(S(C)(=O)=O)cc5)ccn34)cc2)n(CCO[Si](C)(C)C(C)(C)C)n1

HCID68544960

未命名化合物

PROCEDURE

实验过程

Prepare the title compound in a manner analogous to Example 1 from 4-[7-(4-methanesulfonyl-phenyl)-imidazo[1,2-a]pyridin-3-yl]-benzylamine and {5-tert-butyl-2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2H-pyrazol-3-yl}-carbamic acid 2,2,2-trichloro-ethyl ester. MS (ES), m/z 701 (M+1).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-98fbec45c0c64911aa7595d630afa544
来源数据集: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07666879B2
来源说明: uspto-grants-2010_02

反应 SMILES

[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][N:14]3[C:17]([C:20]4[CH:27]=[CH:26][C:23]([CH2:24][NH2:25])=[CH:22][CH:21]=4)=[CH:18][N:19]=[C:13]3[CH:12]=2)=[CH:7][CH:6]=1)(=[O:4])=[O:3].ClC(Cl)(Cl)C[O:31][C:32](=O)[NH:33][C:34]1[N:35]([CH2:43][CH2:44][O:45][Si:46]([C:49]([CH3:52])([CH3:51])[CH3:50])([CH3:48])[CH3:47])[N:36]=[C:37]([C:39]([CH3:42])([CH3:41])[CH3:40])[CH:38]=1>>[C:39]([C:37]1[CH:38]=[C:34]([NH:33][C:32]([NH:25][CH2:24][C:23]2[CH:26]=[CH:27][C:20]([C:17]3[N:14]4[CH:15]=[CH:16][C:11]([C:8]5[CH:7]=[CH:6][C:5]([S:2]([CH3:1])(=[O:3])=[O:4])=[CH:10][CH:9]=5)=[CH:12][C:13]4=[N:19][CH:18]=3)=[CH:21][CH:22]=2)=[O:31])[N:35]([CH2:43][CH2:44][O:45][Si:46]([C:49]([CH3:52])([CH3:51])[CH3:50])([CH3:48])[CH3:47])[N:36]=1)([CH3:42])([CH3:40])[CH3:41]