Benzylamine → HCID 20552833, compound

HRID 1446792Notes

Reaction equation

HRID 1446792 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:8]([O:11][CH2:12][C:13]2[C:14]([O:19][CH3:20])=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:9][CH3:10])[CH:5]=[CH:6][CH:7]=1.[CH2:21]([NH2:28])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:21]([NH:28][CH2:10][CH2:9][CH:8]([C:4]1[CH:5]=[CH:6][CH:7]=[CH:2][CH:3]=1)[O:11][CH2:12][C:13]1[C:14]([O:19][CH3:20])=[CH:15][CH:16]=[CH:17][CH:18]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 22987706HCID 22987706, compound

Product 1

HCID 20552833HCID 20552833, compound

Procedure

A secondary N-benzylamine can likewise be debenzylated to produce the desired primary amine. To prepare such a secondary benzlamine, 3-chloro-1-(o-anisyloxy)propylbenzene or other 1-substituted phenyl-3-chloropropylbenzene, utilized as an intermediate in an earlier procedure, can be reacted with benzylamine to yield N-benzyl 3-phenyl-3-(o-anisyloxy)propylamine.

Sources & evidence

ORD record
ord-d2712516f07743eb8c160545f1ea9b5c
Source dataset
uspto-grants-1982_02
Patent number
US04313896

Reaction notes

Loading…