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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1446807Generated: October 25, 2026

[1,1'-Biphenyl]-3-carbonitrile → 2-[(1,1'-Biphenyl)-3-yl]-1,2,4-triazolo[5,1-a]isoquinoline

https://huagongshe.com/reaction/1446807

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[1,1'-Biphenyl]-3-carbonitrileHCID 34340—
Reactant2-Amino-1(2H)-isoquinolinoneHCID 12383218—
SolventEthyl AcetateHCID 8857—
Product2-[(1,1'-Biphenyl)-3-yl]-1,2,4-triazolo[5,1-a]isoquinolineHCID 1302107649%

Reaction Steps

This compound was prepared according to the procedure of the foregoing Example, starting from 2-amino-isoquinoline-1(2H)-one and 3-phenyl-benzonitrile. Yield 49%. M.p. 167°-69° C. (from ethyl acetate).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04313950
Source datasetuspto-grants-1982_02
ORD IDord-6d1772bc69df4fcaa42033a5f630f922
Source noteuspto-grants-1982_02