HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Acetylthio-2-azetidinone → 1-(Allyloxycarbonylhydroxymethyl)-4-acetylthioazetidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Acetylthio-2-azetidinone | HCID 13132058 | — |
| Reactant | Allyl glyoxylate monohydrate | HCID 21908969 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-(Allyloxycarbonylhydroxymethyl)-4-acetylthioazetidin-2-one | HCID 20552000 | — |
Reaction Steps
4-Acetylthioazetidin-2-one (Annalen, 1974, p. 553) (1.4 g) and allyl glyoxylate hydrate (1.5 g) are refluxed for 2 hours in benzene to afford a solution of 1-(allyloxycarbonylhydroxymethyl)-4-acetylthioazetidin-2-one which is cooled and used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04314942 |
| Source dataset | uspto-grants-1982_02 |
| ORD ID | ord-69d5231ee89e4b2b8e6d0abfde0af1c9 |
| Source note | uspto-grants-1982_02 |