Acetic Anhydride → 3-Acetyloxy-1-propanesulfonic acid sodium salt

HRID 1447067Notes

Reaction equation

HRID 1447067 reaction equation
[Na+:1].[OH:2][CH2:3][CH2:4][CH2:5][S:6]([O-:9])(=[O:8])=[O:7].[C:10](OC(=O)C)(=[O:12])[CH3:11]>>[Na+:1].[C:10]([O:2][CH2:3][CH2:4][CH2:5][S:6]([O-:9])(=[O:8])=[O:7])(=[O:12])[CH3:11]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 236872121-Propanesulfonic acid, 3-hydroxy-, sodium salt (1:1)

Product 1

HCID 588713853-Acetyloxy-1-propanesulfonic acid sodium salt

Procedure

A mixture of 81 g (0.5 mol) of 3-hydroxy-1-propanesulfonic acid sodium salt and 250 ml of acetic anhydride is heated on the steam bath for 64 hrs and at reflux for 2 hrs. The dark solution is cooled and the solid is filtered, washed with ether and dried to give 82.8 g of 3-acetyloxy-1-propanesulfonic acid sodium salt.

Workup

  1. temperatureis heated on the steam bath for 64 hrs
  2. temperatureat reflux for 2 hrs
  3. temperatureThe dark solution is cooled
  4. filtrationthe solid is filtered
  5. washwashed with ether
  6. customdried

Sources & evidence

ORD record
ord-ff283ee98aac4474839c2dfb733a0df6
Source dataset
uspto-grants-1982_02
Patent number
US04315014

Reaction notes

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