HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium → Ethyl 3-hydroxy-4,5-dimethyl-1H-pyrrole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 86738253 | HCID 86738253 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 3-hydroxy-4,5-dimethyl-1H-pyrrole-2-carboxylate | HCID 54680365 | 78.2% |
Reaction Steps
Using the method described in Example 1, 35 g of sodium in 1.5 liters of ethanol, and 264 g of 3-(ethoxycarbonylmethylamino)-2-methylcrotonic acid ethyl ester in 400 ml of ethanol give 165 g of 3-hydroxy-4,5-dimethyl-pyrrole-2-carboxylic acid ethyl ester, of melting point 111°-113° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04315939 |
| Source dataset | uspto-grants-1982_02 |
| ORD ID | ord-11a0e069d43b41a7997f579eb3568033 |
| Source note | uspto-grants-1982_02 |