Acetyl chloride → HCID 13156312, compound

HRID 1447171Notes

Reaction equation

HRID 1447171 reaction equation
[CH:1]1[N:9]2[C:4]([NH:5][NH:6][C:7]3[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=32)=[N:3][N:2]=1.[C:14](Cl)(=[O:16])[CH3:15]>C1(C)C=CC=CC=1>[C:14]([N:6]1[C:7]2[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=2[N:9]2[CH:1]=[N:2][N:3]=[C:4]2[NH:5]1)(=[O:16])[CH3:15]

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 135503117HCID 135503117, compound

Product 1

HCID 13156312HCID 13156312, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of 7.0 g (0.040 mole) of 4,5-dihydro-s-triazolo[3,4-c]benzo-as-triazine, 3.1 g (0.04 mole) of acetyl chloride and 50 ml of toluene is refluxed under nitrogen atmosphere. The reaction mixture is cooled. The title compound, melting at 220° C., is obtained with a yield of 70%. The product does not show melting point depression in admixture with the compound prepared according to Example 8.

Workup

  1. temperatureis refluxed under nitrogen atmosphere
  2. temperatureThe reaction mixture is cooled

Sources & evidence

ORD record
ord-4f804dc52cba47e580180c8dd8826821
Source dataset
uspto-grants-1982_02
Patent number
US04316022

Reaction notes

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