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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1447182Generated: November 1, 2026

Pyridine → 1-benzyl-1H-tetrazole-5-carbonyl chloride

https://huagongshe.com/reaction/1447182

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantOxalyl chlorideHCID 65578—
ReactantPotassium 1-Benzyl-1H-tetrazole-5-carboxylateHCID 23688251—
SolventBenzeneHCID 241—
Product1-benzyl-1H-tetrazole-5-carbonyl chlorideHCID 20463876—

Reaction Conditions

Temperature15 °C

Reaction Steps

The potassium salt produced in Example 2, and pyridine are stirred at 6° C. in benzene followed by rapid addition of oxalyl chloride. After stirring one half hour at 15° C. the mixture is stripped at 15° C., and scrubbed with two portions of benzene at 15° C. to yield 1-benzyl-1H-tetrazole-5-carbonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04316037
Source datasetuspto-grants-1982_02
ORD IDord-a4b8ac2596594edc927b3fef95401b26
Source noteuspto-grants-1982_02