Dimethylformamide → 1-(Azidomethyl)-4-methoxybenzene

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Reaction Steps

p-Methoxybenzyl azide is prepared by stirring a mixture of 35 g. of p-methoxybenzyl chloride and 20 g. of sodium azide in 300 ml. dimethylformamide at room temperature for 30 minutes. The mixture is poured into water and extracted with benzene. The extracts are dried, evaporated to dryness and the residue is vacuum distilled, 34 g., bp 72°-75° C. (0.05 mm) (lit. 118°-118.5° C., 10 mm., reference in example 1).

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