Sodium Hydroxide → Sodium 1-(p-Methoxybenzyl)-1H-tetrazole-5-carboxylate

HRID 1447184Notes

Reaction equation

HRID 1447184 reaction equation
[CH3:1][O:2][C:3]1[CH:19]=[CH:18][C:6]([CH2:7][N:8]2[C:12]([C:13]([O:15]CC)=[O:14])=[N:11][N:10]=[N:9]2)=[CH:5][CH:4]=1.[OH-].[Na+:21]>C(O)C.O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][N:8]2[C:12]([C:13]([O-:15])=[O:14])=[N:11][N:10]=[N:9]2)=[CH:18][CH:19]=1.[Na+:21]

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 11097352ethyl 1-(4-methoxybenzyl)-1H-tetrazole-5-carboxylate

Product 1

HCID 23720170Sodium 1-(p-Methoxybenzyl)-1H-tetrazole-5-carboxylate

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

Following the procedure of Example 2, 1-(p-methoxybenzyl)-5-carboethoxy tetrazole is dissolved in warm absolute ethanol. A slight stoichiometric excess of NaOH in water is added to precipitate the sodium salt.

Workup

  1. customto precipitate the sodium salt

Sources & evidence

ORD record
ord-52d8a831f9474dce8974c788e45afef6
Source dataset
uspto-grants-1982_02
Patent number
US04316037

Reaction notes

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