Acetic Anhydride → HCID 19834543, compound

HRID 1447196Notes

Reaction equation

HRID 1447196 reaction equation
[NH:1]([C:8]1[C:12]([C:13]([O:15][CH3:16])=[O:14])=[C:11]([CH3:17])[NH:10][N:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:18](OC(=O)C)(=[O:20])[CH3:19]>>[C:18]([N:10]1[C:11]([CH3:17])=[C:12]([C:13]([O:15][CH3:16])=[O:14])[C:8]([NH:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[N:9]1)(=[O:20])[CH3:19]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 19834564HCID 19834564, compound

Product 1

HCID 19834543HCID 19834543, compound

Procedure

23 g of 3-anilino-4-methoxycarbonyl-5-methylpyrazole is dissolved in 51 g of acetic anhydride and brought to the boil. After 15 minutes' boiling the mixture is allowed to cool, poured into ice water and stirred for 30 minutes. The solid which separates is isolated and recrystallized from methanol; m.p. 115°-116° C.

Workup

  1. temperatureto cool
  2. customThe solid which separates is isolated
  3. customrecrystallized from methanol

Sources & evidence

ORD record
ord-c36996a6dbbd4feba9d8c6c8109d3b77
Source dataset
uspto-grants-1982_02
Patent number
US04316039

Reaction notes

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