HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidone → 1-Heptylpyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | 1-Bromoheptane | HCID 12369 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-Heptylpyrrolidin-2-one | HCID 12283660 | 31% |
Reaction Steps
Following example 1, on refluxing 13 g of 50% oil dispersion of sodium hydride (6.5 g NaH, 0.271 M), 20.35 g (0.239 M) of azacyclopentan-2-one and 47.28 g (0.264 M) of 1-bromoheptane in dry toluene for 21 hours was obtained 13.6 g (31%) of colorless oil; boiling point 115°-120°/0.6 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04316893 |
| Source dataset | uspto-grants-1982_02 |
| ORD ID | ord-862258e65f9e45ff8ee332d60956b1a5 |
| Source note | uspto-grants-1982_02 |