Methyl iodide → HCID 13103379, compound

Participants

Reaction Steps

The mixture of 500 mg of 2-methyl-1,3,4,14b-tetrahydro-10H-pyrazino[1,2-a]pyrrolo[2,1-c][1,4]benzodiazepine, 10 ml of methylene chloride and 0.5 ml of methyl iodide is stirred at room temperature for one hour. It is filtered and the residue washed with methylene chloride, to yield the 2,2-dimethyl-1,3,4,14b-tetrahydro-10H-pyrazino[1,2-a]pyrrolo[2,1-c][1,4]benzodiazepinium iodide melting at 258°-260° with decomposition.

Provenance & Evidence