HuagongsheHuagongshe Chemistry Print Report · For research reference only
rac-(2R,4S)-4-phenylpyrrolidine-2-carboxylic acid hydrochloride → 4-Phenyl-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | rac-(2R,4S)-4-phenylpyrrolidine-2-carboxylic acid hydrochloride | HCID 51064133 | — |
| Reactant | 3-[[(4-Methoxy)phenylmethyl]thio]-2-methylthiopropionyl chloride | HCID 54225835 | — |
| Product | 4-Phenyl-L-proline | HCID 10313471 | — |
Reaction Steps
The 3-[[(4-methoxy)phenylmethyl]thio]-2-methylthiopropionyl chloride from part (a) is reacted with cis-4-phenyl-L-proline, hydrochloride to yield [1(S),4R]-1-[[(4-methoxy)phenylmethyl]thio]-2-methylthio-1-oxopropyl]-4-phenyl-L-proline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04316905 |
| Source dataset | uspto-grants-1982_02 |
| ORD ID | ord-35f63ce70f5d4f52a185dac1316501d1 |
| Source note | uspto-grants-1982_02 |