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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1447446Generated: October 25, 2026

Sodium Carbonate → 1-(3-acetylthio-1-oxopropyl)-cis-4-methoxy-L-proline

https://huagongshe.com/reaction/1447446

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium CarbonateHCID 10340—
Reactant3-Chloropropyl thioacetateHCID 83044—
Reactant(2S,4S)-4-methoxypyrrolidine-2-carboxylic acidHCID 12849452—
Product1-(3-acetylthio-1-oxopropyl)-cis-4-methoxy-L-prolineHCID 22819374—

Reaction Steps

Following the procedure of Example 1 (d), cis-4-methoxy-L-proline is treated with a solution of 3-acetylthiopropyl chloride in the presence of sodium carbonate to yield 1-(3-acetylthio-1-oxopropyl)-cis-4-methoxy-L-proline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04316906
Source datasetuspto-grants-1982_02
ORD IDord-a9ac93956cc14db980a458a1e84a433c
Source noteuspto-grants-1982_02