Ammonia → 1-(3-mercapto-1-oxopropyl)-cis-4-methoxy-L-proline

HRID 1447447Notes

Reaction equation

HRID 1447447 reaction equation
C([S:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:16][C@@H:15]([O:17][CH3:18])[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8])(=O)C.N>>[SH:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:16][C@@H:15]([O:17][CH3:18])[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 228193741-(3-acetylthio-1-oxopropyl)-cis-4-methoxy-L-proline

Product 1

HCID 128494581-(3-mercapto-1-oxopropyl)-cis-4-methoxy-L-proline

Procedure

The 1-(3-acetylthio-1-oxopropyl)-cis-4-methoxy-L-proline is hydrolyzed with an aqueous solution of ammonia according to the procedure of Example 2 to yield 1-(3-mercapto-1-oxopropyl)-cis-4-methoxy-L-proline.

Sources & evidence

ORD record
ord-f052a44c07084a6f912a49207d540e7f
Source dataset
uspto-grants-1982_02
Patent number
US04316906

Reaction notes

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