Ammonia → HCID 22819376, compound

HRID 1447452Notes

Reaction equation

HRID 1447452 reaction equation
C([S:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:16][C@@H:15]([O:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8])(=O)C.N>>[SH:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:16][C@@H:15]([O:17][C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 22819375HCID 22819375, compound

Product 1

HCID 22819376HCID 22819376, compound

Procedure

Hydrolysis of 1-[3-(acetylthio)-1-oxopropyl]-cis-4-phenoxy-L-proline with an aqueous ammonia solution according to the procedure of Example 2 yields 1-(3-mercapto-1-oxopropyl)-cis-4-phenoxy-L-proline.

Sources & evidence

ORD record
ord-8f8a436f51d249c396d803a9f206de68
Source dataset
uspto-grants-1982_02
Patent number
US04316906

Reaction notes

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