Ammonia → HCID 22819370, compound

HRID 1447453Notes

Reaction equation

HRID 1447453 reaction equation
C([S:4][CH2:5][C:6]([N:8]1[CH2:15][C@@H:14]([O:16][C:17]2[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=2)[CH2:13][C@H:9]1[C:10]([OH:12])=[O:11])=[O:7])(=O)C.N>>[SH:4][CH2:5][C:6]([N:8]1[CH2:15][C@@H:14]([O:16][C:17]2[CH:18]=[CH:19][C:20]([O:23][CH3:24])=[CH:21][CH:22]=2)[CH2:13][C@H:9]1[C:10]([OH:12])=[O:11])=[O:7]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 22819369HCID 22819369, compound

Product 1

HCID 22819370HCID 22819370, compound

Procedure

Hydrolysis of 1-[2-(acetylthio)-1-oxoethyl]-cis-4-(4-methoxyphenoxy)-L-proline with an aqueous ammonia solution according to the procedure of Example 2 yields 1-(2-mercapto-1-oxoethyl)-cis-4-(4-methoxyphenoxy)-L-proline.

Sources & evidence

ORD record
ord-b741d8017a594bb7b6730c7b48a552d1
Source dataset
uspto-grants-1982_02
Patent number
US04316906

Reaction notes

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