Ammonia → HCID 53984779, compound

HRID 1447455Notes

Reaction equation

C([O:4][C:5]1[CH:10]=[CH:9][C:8]([S:11][C@@H:12]2[CH2:16][N:15]([C:17](=[O:24])[CH2:18][CH2:19][S:20]C(=O)C)[C@H:14]([C:25]([OH:27])=[O:26])[CH2:13]2)=[CH:7][CH:6]=1)(=O)C.N>>[OH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11][C@@H:12]2[CH2:16][N:15]([C:17](=[O:24])[CH2:18][CH2:19][SH:20])[C@H:14]([C:25]([OH:27])=[O:26])[CH2:13]2)=[CH:7][CH:6]=1

Participants

Reactant 2

HCID 222Ammonia

HCID 54558093HCID 54558093, compound

Product 1

HCID 53984779HCID 53984779, compound

Procedure

Hydrolysis of (cis)-4-(4-acetyloxyphenylthio)-1-[3-(acetylthio)-1-oxopropyl]-L-proline with an aqueous ammonia solution according to the procedure of Example 2 yields (cis)-4-(4-hydroxyphenylthio)-1-(3-mercapto-1-oxopropyl)-L-proline.

Sources & evidence

ORD record: ord-c563ebf6aa5e4124a18799749cb1ece0
Source dataset: uspto-grants-1982_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04316906

Reaction notes

Loading…