HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 1-(1,3,4-Thiadiazol-2-yl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 1-Piperazinecarboxaldehyde | HCID 82191 | — |
| Reactant | 2-Bromo-1,3,4-thiadiazole | HCID 2795198 | — |
| Product | 1-(1,3,4-Thiadiazol-2-yl)piperazine | HCID 20234069 | — |
Reaction Steps
The starting 1-(1,3,4-thiadiazol-2-yl)-piperazine was prepared by hydrolyzing with alcoholic potassium hydroxide the crude formyl derivative, itself prepared by condensing 1-formyl piperazine with 2-bromo-1,3,4-thiadiazole melting at 74° C. (Goerdeler and al., Ber 89 1534 (1956)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04177272 |
| Source dataset | uspto-grants-1979_12 |
| ORD ID | ord-9e58822d7c0d4b0191de488e537d79db |
| Source note | uspto-grants-1979_12 |